Tag Archives: Surgery (Orthopeadics)

Baby’s life saved with groundbreaking 3-D printed tracheal splint that restored his airway

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Every day, their baby stopped breathing, his collapsed bronchus blocking the crucial flow of air to his lungs. April and Bryan Gionfriddo watched helplessly, just praying that somehow the dire predictions weren’t true. “Quite a few doctors said he had a good chance of not leaving the hospital alive,” says April Gionfriddo, about her now […]

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Nasal lining used to breach blood/brain barrier

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Neurodegenerative and central nervous system (CNS) diseases represent a major public health issue affecting at least 20 million children and adults in the United States alone. Multiple drugs exist to treat and potentially cure these debilitating diseases, but 98 percent of all potential pharmaceutical agents are prevented from reaching the CNS directly due to the […]

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Hundreds of tiny untethered surgical tools deployed in first animal biopsies

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By using swarms of untethered grippers, each as small as a speck of dust, Johns Hopkins engineers and physicians say they have devised a new way to perform biopsies that could provide a more effective way to access narrow conduits in the body as well as find early signs of cancer or other diseases. In […]

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‘Sharps’ injuries have major health and cost impact for surgeons

Injuries caused by needles and other sharp instruments are a major occupational hazard for surgeons — with high costs related to the risk of contracting serious infectious diseases, according to a special article in the April issue of Plastic and Reconstructive Surgery, the official medical journal of the American Society of Plastic Surgeons (ASPS). ASPS […]

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Fallout from nuclear testing shows that the Achilles tendon can’t heal itself

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Notorious among athletes and trainers as career killers, Achilles tendon injuries are among the most devastating. Now, by carbon testing tissues exposed to nuclear fallout in post WWII tests, scientists have learned why: Like our teeth and the lenses in our eyes, the Achilles tendon is a tissue that does not repair itself. This discovery […]

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Stem cells boost heart’s natural repair mechanisms

Injecting specialized cardiac stem cells into a patient’s heart rebuilds healthy tissue after a heart attack, but where do the new cells come from and how are they transformed into functional muscle? Researchers at the Cedars-Sinai Heart Institute, whose clinical trial results in 2012 demonstrated that stem cell therapy reduces scarring and regenerates healthy tissue […]

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Stem cells found to heal damaged artery in lab study in baboons

Scientists at the Texas Biomedical Research Institute in San Antonio have for the first time demonstrated that baboon embryonic stem cells can be programmed to completely restore a severely damaged artery. These early results show promise for eventually developing stem cell therapies to restore human tissues or organs damaged by age or disease. “We first […]

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Gastric bypass surgery alters gut microbiota profile along the intestine

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Research to be presented at the Annual Meeting of the Society for the Study of Ingestive Behavior (SSIB) finds that gastric bypass surgery induces changes in the gut microbiota and peptide release that are similar to those seen after treatment with prebiotics. Previous animal research demonstrated that ingestion of a high-fat diet produces weight gain […]

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Brain researchers start mapping the Human ‘Connectome’

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A research effort called the Human Connectome Project is seeking to explore, define, and map the functional connections of the human brain. An update on progress in and upcoming plans for the Human Connectome Project appears in the July issue of Neurosurgery, official journal of the Congress of Neurological Surgeons. Analogous to the Human Genome […]

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Seeing inside tissue for no-cut surgeries: Researchers develop technique to focus light inside biological tissue

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Imagine if doctors could perform surgery without ever having to cut through your skin. Or if they could diagnose cancer by seeing tumors inside the body with a procedure that is as simple as an ultrasound. Thanks to a technique developed by engineers at the California Institute of Technology (Caltech), all of that may be […]

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Laser scalpels get ultrafast, ultra-accurate, and ultra-compact makeover

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Whether surgeons slice with a traditional scalpel or cut away with a surgical laser, most medical operations end up removing some healthy tissue, along with the bad. This means that for delicate areas like the brain, throat, and digestive tract, physicians and patients have to balance the benefits of treatment against possible collateral damage. To […]

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Botox injections now used for severe urinary incontinence

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When you think of Botox injections, you probably think of getting rid of unwanted wrinkles around the eyes or forehead, but recently the US Food and Drug Administration (FDA) approved using the injections to help patients with neurological conditions who suffer from incontinence, or an overactive bladder. Botox injections paralyze the bladder muscle to prevent […]

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Delay in surgery can cause irreparable meniscus tears in children with ACL injuries

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For children aged 14 and under, delaying reconstructive surgery for anterior cruciate ligament (ACL) injuries may raise their risk of further injury, according to a new study by pediatric orthopaedic surgeons. If surgery occurs later than 12 weeks after the injury, the injury may even be irreparable. “Treating ACL injuries in these children is controversial, […]

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Building bone from cartilage

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A person has a tumor removed from her femur. A soldier is struck by an improved explosive device and loses a portion of his tibia. A child undergoes chemotherapy for osteosarcoma but part of the bone dies as a result. Every year, millions of Americans sustain fractures that don’t heal or lose bone that isn’t […]

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Potential biomarker for osteoarthritis identified

Researchers have identified for the first time two molecules that hold promise as a biomarker for measuring cartilage damage associated with osteoarthritis. The concentration of two molecules called non-coding RNAs in blood were associated with mild cartilage damage in 30 patients who were one year removed from reconstruction surgery to repair an anterior cruciate ligament, […]

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Discovery uses ‘fracture putty’ to repair broken bone in days

Broken bones in humans and animals are painful and often take months to heal. Studies conducted in part by University of Georgia Regenerative Bioscience Center researchers show promise to significantly shorten the healing time and revolutionize the course of fracture treatment. “Complex fractures are a major cause of amputation of limbs for U.S. military men […]

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Headed for surgery? Hold the protein

A new study suggests that in mice, cutting protein from the diet for a week can protect organs that might otherwise be damaged by injury or surgery. That’s a common recommendation doctors give patients to ensure a safe procedure. Now a new study in mice suggests that the advice may have benefits beyond the operation […]

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Revolutionary surgical technique for treating perforations of the eardrum

A revolutionary surgical technique for treating perforations of the tympanic membrane (eardrum) in children and adults has been developed at the Sainte-Justine University Hospital Centre, an affiliate of the Universit√© de Montreal, by Dr. Issam Saliba. The new technique, which is as effective as traditional surgery and far less expensive, can be performed in 20 […]

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Gunshot, stabbing victims are recovering without exploratory surgery

Although more patients with abdominal gunshot and stab wounds can successfully forego emergency “exploratory” surgery and its potential complications, new Johns Hopkins research suggests that choosing the wrong patients for this “watchful waiting” approach substantially increases their risk of death from these injuries. “Managing gunshot and stab wounds without exploratory surgery prevents complications, saves money […]

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Less blood needed post-surgery, new study suggests

Patients need less blood after surgery than is widely thought. A new study comparing two plans for giving blood transfusions following surgery showed no ill effects from postponing transfusion until patients develop signs of anemia or their hemoglobin concentration falls below 8 g/dL. Results of the National Heart and Lung and Blood Institute- funded study […]

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New bandage spurs, guides blood vessel growth

Researchers have developed a bandage that stimulates and directs blood vessel growth on the surface of a wound. The bandage, called a “microvascular stamp,” contains living cells that deliver growth factors to damaged tissues in a defined pattern. After a week, the pattern of the stamp “is written in blood vessels,” the researchers report. A […]

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Earlier tracheostomies after head injuries result in better patient outcomes

A tracheostomy performed within the first seven days after a severe head injury results in better overall patient outcome, according to a team of Penn State College of Medicine researchers. This is especially true for patients who have a greater chance of surviving when admitted to the hospital. “The CDC estimates that more than 200,000 […]

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Glowing cells guide cancer surgeons

Most malignant ovarian tumours express high numbers of receptors for the molecule folate (also known as vitamin B9), so by attaching the fluorescent molecule fluorescein iso-thiocyanate to folate, researchers created a cancer-cell probe. After injecting this into patients, labelled cells were made to glow white with a special camera and light, allowing surgeons to spot […]

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Sutureless method for joining blood vessels invented

Reconnecting severed blood vessels is mostly done the same way today — with sutures — as it was 100 years ago, when the French surgeon Alexis Carrel won a Nobel Prize for advancing the technique. Now, a team of researchers at the Stanford University School of Medicine has developed a sutureless method that appears to […]

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Use adult stem cells to grow neck vertebrae

Neurosurgery researchers at UC Davis Health System have used a new, leading-edge stem cell therapy to promote the growth of bone tissue following the removal of cervical discs — the cushions between the bones in the neck — to relieve chronic, debilitating pain. The procedure was performed by associate professors of neurosurgery Kee Kim and […]

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Incisionless surgery now available as an investigational treatment for esophageal disorder

The procedure is one of a growing number of surgeries to use the body’s natural orifices as an entry point, thus eliminating the need for traditional incisions. Northwestern Memorial Hospital is one of only a few centers in the U.S. with surgeons trained to perform the procedure. “This surgical approach not only eliminates the need […]

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Surgeon shows simple cotton swab slashes post-surgical wound infections

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A simple item found in almost every medicine cabinet — a cotton swab — may be a key tool in the fight against post-surgical wound infections. In a sentinel trial, Cedars-Sinai Medical Center surgeon Shirin Towfigh, MD, showed that painless and gentle probing of a wound with a dry cotton swab after surgery dramatically reduced […]

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Artificial tissue promotes skin growth in wounds

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Victims of third-degree burns and other traumatic injuries endure pain, disfigurement, invasive surgeries and a long time waiting for skin to grow back. Improved tissue grafts designed by Cornell scientists that promote vascular growth could hasten healing, encourage healthy skin to invade the wounded area and reduce the need for surgery. These so-called dermal templates […]

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Hospitals misleading patients about benefits of robotic surgery, study suggests

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An estimated four in 10 hospital websites in the United States publicize the use of robotic surgery, with the lion’s share touting its clinical superiority despite a lack of scientific evidence that robotic surgery is any better than conventional operations, a new Johns Hopkins study finds. The promotional materials, researchers report online in the Journal […]

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Bone marrow cells that transform into skin cells could revolutionize approach to wound treatment

Researchers at King’s College London and Osaka University in Japan have identified specific bone marrow cells that can transform into skin cells to repair damaged skin tissue, according to a study published in Proceedings of the National Academy of Sciences (PNAS). The team has uncovered how this process works, providing new insights into the mechanisms […]

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